Lu, Chia-Sing
Shiau, Ai-Li
Su, Bing-Hua
Hsu, Tsui-Shan
Wang, Chung-Teng
Su, Yu-Chu
Tsai, Ming-Shian
Feng, Yin-Hsun
Tseng, Yau-Lin
Yen, Yi-Ting
Wu, Chao-Liang
Shieh, Gia-Shing https://orcid.org/0000-0003-2480-4313
Funding for this research was provided by:
National Science Council (NSC 98-2320-B-006-030-MY3, NSC 100-3112-B-006-003)
Article History
Received: 21 October 2019
Accepted: 28 April 2020
First Online: 1 June 2020
Ethics approval and consent to participate
: Two cohorts of different hospitals were collected from patients with lung adenocarcinoma at the Thoracic Division, Department of Surgery, National Cheng Kung University (NCKU) Hospital, and Department of Pathology of Chi-Mei Medical Center, Tainan, Taiwan. In the cohort from NCKU Hospital, informed consent was obtained from all subjects, and the experimental protocol was approved by the Institutional Review Board (IRB), NCKU Hospital (IRB number: B-ER-105-406). Another cohort with a total of 84 patients diagnosed with lung cancer between September 1998 and March 2010 at the Department of Pathology of Chi-Mei Medical Center was included, and the study was approved by the IRB of the Chi-Mei Medical Center (approval no. 10308-002). The condition of inform consent was a waiver documentation of consent, based on the protection of patient identifiable information.
: All authors agreed on the manuscript.
: No potential conflicts of interest were disclosed.