Document is current

Article History

Received: 30 January 2021

Accepted: 3 April 2021

First Online: 26 April 2021

Declarations

:

: AML bone marrow (BM) samples were obtained from donors and patients at the City of Hope National Medical Center, under one of four City of Hope Institutional Review Board-approved banking protocols (#06229, #03162, #07047 or #18067) in accordance with assurances filed with and approved by the Department of Health and Human Services, and meeting all requirements of the Declaration of Helsinki. Written informed consent was obtained from donors (#06229) or patients (#03162, #07047 or #18067) prior to specimen acquisition. Animal care and experimental procedures were performed in accordance with approved protocols from the Institutional Animal Care and Use Committee at the City of Hope National Medical Center. All animal studies were performed in accordance with the guidelines of the City of Hope Research Animal Care Committee.

: Not applicable.

: VP: <i>Dova</i>: Consultancy and Honoraria; <i>Amgen:</i> Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees and Speakers Bureau; <i>Servier:</i> Membership on an entity's Board of Directors or advisory committees and Speakers Bureau; <i>Novartis:</i> Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees and Speakers Bureau; <i>Jazz Pharmaceuticals:</i> Membership on an entity's Board of Directors or advisory committees and Speakers Bureau; <i>Pfizer:</i> Membership on an entity's Board of Directors or advisory committees and Speakers Bureau; <i>Genetech:</i> Membership on an entity's Board of Directors or advisory committees and Speakers Bureau; <i>AbbVie, Inc.:</i> Membership on an entity's Board of Directors or advisory committees and Speakers Bureau. SR: <i>Celgene:</i> Speakers Bureau; <i>NeoGenomics:</i> Consultancy; <i>Seattle Genetics:</i> Consultancy; <i>Aileron Therapeutics:</i> Consultancy; <i>Novartis:</i> Consultancy; <i>Paradigm Medical Communications:</i> Speakers Bureau; <i>Abbvie:</i> Speakers Bureau; <i>Pebromene:</i> Consultancy. GM: <i>Iaso Bio:</i> Membership on an entity's Board of Directors or advisory committees; <i>Abbvie:</i> Speakers Bureau; <i>Novartis:</i> Speakers Bureau; <i>Pfizer:</i> Other: Research Support (Investigation Initiated Clinical Trial); <i>Merck:</i> Other: Research Support (Investigation Initiated Clinical Trial); <i>Takeda:</i> Other: Research Support (Investigation Initiated Clinical Trial). VG: <i>Abbvie:</i> Sponsored Research Support. <i>Sunesis</i>: Sponsored Research Support. <i>LOXO</i>: Sponsored Research Support. <i>Dava Oncology</i>: Speakers Bureau. <i>ClearCreek Bio</i>: Consultancy; Sponsored Research Support. <i>AstraZeneca</i>: Sponsored Research Agreement; Honoraria.