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Authors
Zhang, Xiaomei
Lu, Wenyi
Zhang, Wenjun
He, Xiaoyuan
Zhang, Yu
Jin, Xin
Zhang, Meng
Wang, Yingshuai
Guan, Xuwen
Zhang, Rui
Wang, Bing
Lyu, Hairong
Xiao, Xia
Bai, Xue
Pu, Yedi
Meng, Juanxia
Zhu, Haibo
Wang, Zhao
Zhang, Huan
Lyu, Cuicui
Zhang, Hongkai
Liang, Aibin
Zhao, Mingfeng
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Funding
Funding for this research was provided by:
National Natural Sciences Foundation of China (82570274)
National Natural Sciences Foundation of China (82570277)
the Science and Technology Project of Tianjin Municipal Health Committee (TJWJ2022QN030)
the Science and Technology Project of Tianjin Municipal Health Committee (TJWJ2024QN040)
the Science and Technology Project of Tianjin Municipal Health Committee (TJWJ2023QN027)
the Science and Technology Project of Tianjin Municipal Health Committee (TJWJ2025MS011)
the Science and Technology Project of Tianjin Municipal Health Committee (TJWJ2023XK010)
the Science and Technology Project of Tianjin Municipal Health Committee (TJWJ2022XK018)
Beijing Natural Science Foundation (7254351)
major special project on public health science and technology in Tianjin (24ZXGZSY00120)
Tianjin Key Medical Discipline (Specialty) Construction Project (TJWJ2023XK010)
Tianjin Key Clinical Specialty Construction Project and Tianjin Key Medical Discipline Construction Project (TJYXZDXK-3-001A-004)
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Article History
Received: 2 September 2025
Accepted: 6 November 2025
First Online: 18 December 2025
Declarations
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: The study was performed in accordance with the Declaration of Helsinki and in compliance with good clinical practice guidelines and applicable laws. The protocol was approved by the institutional review board at study sites. Written informed consent was obtained before study entry from each patient or from the patient’s legally authorized representative if the patient was unable to provide consent.
: Not applicable.
: The authors declare no competing interests.
