Funding for this research was provided by:
National Natural Science Foundation of China (81471946,81661148057, 81602417, 81671997, 81572683, 81371827, 81872270,31171307)
Natural Science Foundation of Chongqing (cstc2015jcyjBX0011, cstc2018jcyjAX0254)
Department of S and T for Social Development (2012ZX10002005-003-002, 2017ZX10202203-004)
Received: 24 October 2018
Accepted: 7 January 2019
First Online: 4 February 2019
Ethics approval and consent to participate
: All patients were provided informed consent, and this study was conducted with the approval of Institutional Ethical Review Board of Chongqing Medical University (project license number: 2017012). All animal experiments were conducted according to the guidelines of the Institutional Animal Care and Use Committee at Chongqing Medical University (The project license number: 2017012), and protocols of animal care and use adhere to National Regulations of the administration of laboratory animals.
: All contributing authors agree to the publication of this article.
: The authors declare that they have no competing of interest.
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