De Angelis, Maria Laura
Francescangeli, Federica
Nicolazzo, Chiara
Signore, Michele
Giuliani, Alessandro
Colace, Lidia
Boe, Alessandra
Magri, Valentina
Baiocchi, Marta
Ciardi, Antonio
Scarola, Francesco
Spada, Massimo
La Torre, Filippo
Gazzaniga, Paola
Biffoni, Mauro
De Maria, Ruggero
Zeuner, Ann http://orcid.org/0000-0002-8295-3715
Funding for this research was provided by:
Associazione Italiana per la Ricerca sul Cancro (AIRC IG 2017 Ref: 20744)
Sapienza Università di Roma (RM11916B31436754)
Article History
Received: 8 September 2021
Accepted: 18 January 2022
First Online: 8 March 2022
Declarations
:
: CRC specimens were obtained from patients undergoing surgical resection upon informed consent and approval by La Sapienza-Policlinico Umberto I Ethical Committee (RIF.CE: 410717/10/2016). Peripheral blood samples were obtained from 6 patients with metastatic CRC at baseline before initiation of treatment at Policlinico Umberto I of Rome according to the protocol approved by Ethical Committee of Policlinico Umberto I of Rome (protocol n. 668/09, July 09, 2009; amended protocol 179/16, March 01, 2016). All animal procedures were performed according to the Italian National animal experimentation guidelines (D.L.116/92) upon approval of the experimental protocol by the Italian Ministry of Health’s Animal Experimentation Committee (DM n. 292/2015 PR 23/4/2015).
: Not applicable.
: The authors declare that they have no conflict of interest.