Liu, Daniel S.K.
Puik, Jisce R.
Patel, Bhavik Y.
Venø, Morten T.
Vahabi, Mahrou
Prado, Mireia Mato
Webber, Jason P.
Rees, Eleanor
Upton, Flora M.
Bennett, Kate
Blaker, Catherine
Immordino, Benoit
Comandatore, Annalisa
Morelli, Luca
Sivakumar, Shivan
Swijnenburg, Rutger-Jan
Besselink, Marc G.
Jiao, Long R.
Kazemier, Geert
Giovannetti, Elisa http://orcid.org/0000-0002-7565-7504
Krell, Jonathan
Frampton, Adam E.
Funding for this research was provided by:
Jon Moulton Charity Trust (Jon Moulton Charity Trust)
Action Against Cancer (Action Against Cancer, Action Against Cancer, Action Against Cancer, Action Against Cancer, Action Against Cancer, Action Against Cancer, Action Against Cancer)
Royal College of Surgeons of Edinburgh (Royal College of Surgeons of Edinburgh)
Royal College of Surgeons of England (Royal College of Surgeons of England, Royal College of Surgeons of England)
Mason Medical Research Trust (Mason Medical Research Trust)
S.A.L. Charitable Fund (S.A.L. Charitable Fund)
BRIGHT Cancer Charity (BRIGHT Cancer Charity, BRIGHT Cancer Charity)
Bennink Foundation (Bennink Foundation, Bennink Foundation, Bennink Foundation)
Italian Association of Cancer Research AIRC (Italian Association of Cancer Research AIRC)
Fondazione Pisa (PANOMIC grant)
KWF Kankerbestrijding (KWF Kankerbestrijding, KWF Kankerbestrijding, KWF Kankerbestrijding)
Article History
Received: 27 February 2024
Accepted: 6 June 2024
First Online: 8 July 2024
Declarations
:
: Ethical approval was obtained from Imperial College Healthcare Tissue Bank for the collection and storage and analysis of patient samples (SUR_AF_17_044, “Molecular Detection and Stratification of HPB Cancers”); and the ethical board of the University of Pisa (protocol#23744). All investigations have been performed in accordance with the principles of the Declaration of Helsinki. Written informed consent was obtained from all participants included in this study. Permission of healthy/asymptomatic control subjects was granted by the local institutional review boards. These healthy control subjects signed an informed consent and some of the samples analysed have been featured in previously published studies [, ].
: Not applicable.
: J.K. has received honoraria from Clovis Oncology, Tesaro and AstraZeneca, outside the submitted work. None of the aforementioned companies had any input into the study design, data collection, reporting or preparation of the manuscript. The authors, therefore, have declared that no relevant competing interest exists.