Bajpai, Prachi
Agarwal, Sumit
Afaq, Farrukh
Al Diffalha, Sameer
Chandrashekar, Darshan S.
Kim, Hyung-Gyoon
Shelton, Abigail
Miller, C. Ryan
Singh, Santosh K.
Singh, Rajesh
Varambally, Sooryanarayana
Nagaraju, Ganji Purnachandra
Manne, Ashish
Paluri, Ravi
Khushman, Moh’d
Manne, Upender
Article History
Received: 5 February 2024
Accepted: 22 June 2024
First Online: 11 July 2024
Declarations
:
: Frozen archival CRC tissues, and their uninvolved adjacent noncancerous/tissue specimens, were procured from the tissue biorepository through the Anatomic Pathology Division of the University of Alabama at Birmingham (UAB). Following guidelines described by the Declaration of Helsinki, Institutional Review Board (IRB#090513004) approval from UAB was obtained for experimental use of specimens. For generation of PDX, histologically confirmed colon cancer tissue, obtained from the Department of Surgery at UAB, were procured, and was used after approval of the UAB Institutional Animal Care and Use Committee (Animal Project Number (APN): IACUC-20207). The HT-29 luciferase metastasis experiment in NSG mice, all procedures and experimental protocols were approved and conducted in compliance (IACUC-21501). Syngeneic mouse model where MC38 cells were injected in C57BL/6 mice, all procedures and experimental protocols were approved and conducted in compliance (IACUC-21501).
: Not applicable.
: All authors state that they have no potential conflicts of interest.