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Article History

Received: 30 August 2024

Accepted: 21 January 2025

First Online: 30 January 2025

Declarations

:

: The study involving human participants was conducted by the ethical standards of the Institutional Review Board (IRB) of Xiangya Hospital, Central South University, China, and was approved under the study ID: 201903078. All participants provided written informed consent prior to their inclusion in the study. The study adhered to ethical guidelines, ensuring that treatment decisions were made independently by the multidisciplinary team (MDT) and were not influenced by the study's objectives. The animal experiments were approved by the Ethics Committee for Experimental Animals of Xiangya Hospital, Central South University, Changsha, China (approval number: 202103520). The experiments complied with internationally accepted principles for the care and use of experimental animals (NRC, 2011).

: All authors have read and approved the final manuscript and consent to publication.

: The authors declare that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest.