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Tie2 activity in cancer associated myofibroblasts serves as novel target against reprogramming of cancer cells to embryonic-like cell state and associated poor prognosis in oral carcinoma patients

Crossref DOI link: https://doi.org/10.1186/s13046-025-03405-8

Published Online: 2025-05-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Mitra, Paromita

Saha, Uday

Stephen, Kingsly Joshua

Prasad, Priyanka

Jena, Subhashree

Patel, Ankit Kumar

BV, Harshavardhan

Mondal, Santosh Kumar

Kurkalang, Sillarine

Roy, Sumitava

Ghosh, Arnab

Roy, Shantanu Saha

Das Sarma, Jayasri

Biswas, Nidhan Kumar

Acharya, Moulinath

Sharan, Rajeev

Arun, Pattatheyil

Jolly, Mohit Kumar

Maitra, Arindam

Singh, Sandeep
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Article History

Received: 5 January 2025

Accepted: 1 May 2025

First Online: 10 May 2025

Declarations

:

: Human subjects were included in this study (EC/GOVT/01/12) after approval obtained from the institutional ethics committee of BRIC-National Institute of Biomedical Genomics (BRIC-NIBMG) and the institutional review board of Tata Medical Center (TMC), Kolkata, India. All animal experiments were done as approved by the animal welfare committee of the IISER Kolkata and BRIC-NIBMG (IISERK/IAEC/2020/014).

: The authors have provided consent for publication.

: The authors declare no competing interests.

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