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HAS1high cancer associated fibroblasts located at the tumor invasion front zone promote oral squamous cell carcinoma invasion via ECM remodeling

Crossref DOI link: https://doi.org/10.1186/s13046-025-03493-6

Published Online: 2025-08-14

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jin, Wanyong

Yu, Qiuya

Yu, Liyuan

Zhou, Ting

Wang, Xiren

Lu, Wanqiu

Zhang, Xiaoxin

Ding, Liang

Hu, Qingang

Ni, Yanhong
Funding

Funding for this research was provided by:

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China (82173159)

Nanjing Medical Science and Technique Development Foundation (ZDX22001)

Cultivation Program for Junior Talents of Nanjing Stomatological School, Medical School of Nanjing University (0222R216)

Nanjing Medical Science and Technology Development Foundation, Nanjing Municipal Health Commission (YKK20151)
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Text and Data Mining valid from 2025-08-14

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Article History

Received: 10 April 2025

Accepted: 28 July 2025

First Online: 14 August 2025

Declarations

:

: This study adhered to all relevant ethical regulations and guidelines. All research involving human participants was approved by the Ethics Committee of Nanjing Stomatological Hospital (Approval No. 2022NL-009(KS)), and written informed consent was obtained from all participants prior to study initiation. The study was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki.All animal experiments were approved by the Animal Welfare and Ethics Review Committee of Nanjing University and conducted in accordance with the regulations of the Jiangsu Province Experimental Animal Science Association (Authorization No. 320230075), ensuring strict compliance with animal welfare standards.

: Not applicable.

: The authors declare no competing interests.

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