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Authors
Aljahdali, Ieman A. M.
Ling, Xiang
Wu, Wenjie
Wang, Wenchao
Li, Dan
Zhang, Renyuan
Zhang, Emma
Stablewski, Aimee
Azrak, Rami
Li, Qingyong
Li, Fengzhi
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Funding
Funding for this research was provided by:
PhD student tuition grant (Not applicable)
PhD student tuition grant (Not applicable)
NIH/NCI Grants (R43CA221389)
NIH/NCI Grants (R43CA221389)
Zhejiang Provincial Natural Science Foundation of China (LQ23H300008)
National Key Research and Development Program of China (2022YFC2804104)
China Postdoctoral Science Foundation (2022M712823)
Pancreatic Cancer Action Network (24-CAT-LIFZ)
Mesothelioma Applied Research Foundation Grant (Not applicable)
Pancreatic Cancer Action Network (PanCAN) Translational Research Grant (20-65-FENG)
donation funds from cancer patients and their family members (Not applicable)
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Article History
Received: 29 May 2025
Accepted: 16 September 2025
First Online: 21 October 2025
Declarations
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: Competing interests: FL118 and FL118 core structure-based analogues will be further developed in Canget BioTekpharma LLC ( ), a Roswell Park Cancer Institute spinoff company. FL and XL are two of the initial eighteen investors of Canget to develop FL118 and FL118 core structure-relevant anticancer agents. FL is a full-time employee at Roswell Park Comprehensive Cancer Center (RPCCC) with an adjunct role acting as Chief Scientific Officer (CSO) in the Roswell Park spinoff Canget. FL has a conflict of interest (COI) management plan in place with Roswell Park.
: Not applicable.
: Not applicable.
: FL118 and FL118 core structure-based analogues will be further developed in Canget BioTekpharma LLC ( ), a Roswell Park Cancer Institute spinoff company. FL and XL are two of the initial eighteen investors of Canget to develop FL118 and FL118 core structure-relevant anticancer agents. FL is a full-time employee at Roswell Park Comprehensive Cancer Center (RPCCC) with an adjunct role acting as Chief Scientific Officer (CSO) in the Roswell Park spinoff Canget. FL has a conflict of interest (COI) management plan in place with Roswell Park.
