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Klf4-Tymp axis promotes inflammation-driven early tumorigenesis by enhancing kras mutation-induced acinar-to-ductal metaplasia through Pi3k/Akt and Mek/Erk pathways

Crossref DOI link: https://doi.org/10.1186/s13046-026-03712-8

Published Online: 2026-05-07

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yuan, Qihang

Chen, Junhong

Luo, Peng

Liu, Kai

Guo, Fangyue

Xu, Yao

Tong, Mengying

Xiang, Hong

Shang, Dong
License Information

Text and Data Mining valid from 2026-05-07

Accepted Manuscript valid from 2026-05-07
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Article History

Received: 12 November 2025

Accepted: 7 April 2026

First Online: 7 May 2026

Declarations

:

: All animal experiments were reviewed and approved by the Institutional Animal Care and Use Committee of Dalian Medical University (No. XL250425035) and First Hospital of Jilin University (No. 20250925-01).

: Not applicable.

: The authors declare no competing interests.

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