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Mitochondrial Complex III and IV deficiencies in Leigh Syndrome: Genetic spectrum and Molecular Dynamics simulation study in a pediatric Indian cohort

Crossref DOI link: https://doi.org/10.1186/s13052-026-02355-x

Published Online: 2026-09-30

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Saha, Debolina

Shekhar, Bipin Raj

Kothari, Sonam

Kulkarni, Shilpa Duttaprasanna

Menon, Shyla Ravindran

Das, Dhanjit Kumar https://orcid.org/0000-0003-3237-6224
Funding

Funding for this research was provided by:

Indian Council of Medical Research (F. No.45/05/2022/HUM/BMS)

Indian Council of Medical Research (Intramural)
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Text and Data Mining valid from 2026-09-30

Accepted Manuscript valid from 2026-09-30
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Article History

Received: 29 October 2025

Accepted: 19 September 2026

First Online: 30 September 2026

Declarations

Ethics approval and consent: The study was approved by the Institutional Ethics Committee of ICMR-NIRWoH (436/2021) and Bai Jerbai Wadia Hospital for Children (IEC-BJWHC/19/2019), Mumbai, India. Written informed consent were taken from all the parents/ guardians.

Conflict of interest: None of the authors have declared any conflict of interest.

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