Funding for this research was provided by:
Chinese Academy of Medical Sciences Initiative for Innovative Medicine (CAMS-2017-I2M-1-002)
Article History
Received: 1 February 2019
Accepted: 4 September 2019
First Online: 10 September 2019
Ethics approval and consent to participate
: This study was approved by the Institutional Review Board of Peking Union Medical College Hospital (Registration No. ZS-1245 and HS-1474 for genetic tests and risk-reducing surgeries, respectively). The Chinese Human Genetic Resources Management Office of the National Ministry of Science and Technology approved this study (registration No. [2017]1901, ExternalRef removed). All family members provided informed consent.
: Written consent to publish this information was obtained from the study participants.
: The authors declare that they have no competing interests.