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Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels

Crossref DOI link: https://doi.org/10.1186/s13054-019-2418-5

Published Online: 2019-04-11

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Dekker, Nicole A. M. http://orcid.org/0000-0002-0300-3026
van Leeuwen, Anoek L. I.

van Strien, Willem W. J.

Majolée, Jisca

Szulcek, Robert

Vonk, Alexander B. A.

Hordijk, Peter L.

Boer, Christa

van den Brom, Charissa E.
Funding

Funding for this research was provided by:

Hartstichting (2016T064)

Netherlands Cardiovascular Research Initiative Grant (Grant number 2012-08)

European Society of Anaesthesiology (Research Project Grant 2016)

European Society of Intensive Care Medicine (Levi-Montalcini Award 2017)

Dutch Society of Anesthesiology (Young Investigator Grant 2017)
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Article History

Received: 19 November 2018

Accepted: 1 April 2019

First Online: 11 April 2019

Ethics approval and consent to participate

: The <i>Glycar</i> study was approved in the Netherlands by the Human Subjects Committee of the Amsterdam University Medical Centers under committee’s reference number 13.291 (Clinical trial registration: NTR4212). Written informed consent was obtained from all patients before inclusion.

: Not applicable.

: The authors declare that they have no competing interests.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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