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Authors
Fronczek, Jakub
Polok, Kamil
de Lange, Dylan W.
Jung, Christian
Beil, Michael
Rhodes, Andrew
Fjølner, Jesper
Górka, Jacek
Andersen, Finn H.
Artigas, Antonio
Cecconi, Maurizio
Christensen, Steffen
Joannidis, Michael
Leaver, Susannah
Marsh, Brian
Morandi, Alessandro
Moreno, Rui
Oeyen, Sandra
Agvald-Öhman, Christina
Bollen Pinto, Bernardo
Schefold, Joerg C.
Valentin, Andreas
Walther, Sten
Watson, Ximena
Zafeiridis, Tilemachos
Sviri, Sigal
van Heerden, Peter Vernon
Flaatten, Hans
Guidet, Bertrand
Szczeklik, Wojciech http://orcid.org/0000-0002-1349-1123
,
Schmutz, R.
Wimmer, F.
Eller, P.
Joannidis, M.
De Buysscher, P.
De Neve, N.
Oeyen, S.
Swinnen, W.
Bollen Pinto, B.
Abraham, P.
Hergafi, L.
Schefold, J. C.
Biskup, E.
Piza, P.
Taliadoros, I.
Fjølner, J.
Dey, N.
Sølling, C.
Rasmussen, B. S.
Christensen, S.
Forceville, X.
Besch, G.
Mentec, H.
Michel, P.
Mateu, P.
Michel, P.
Vettoretti, L.
Bourenne, J.
Marin, N.
Guillot, M.
Aissaoui, N.
Goulenok, C.
Thieulot-Rolin, N.
Messika, J.
Lamhaut, L.
Guidet, B.
Charron, C.
Lauten, A.
Sacher, A. L.
Brenner, T.
Franz, M.
Bloos, F.
Ebelt, H.
Schaller, S. J.
Fuest, K.
Rabe, C.
Dieck, T.
Steiner, S.
Graf, T.
Nia, A. M.
Jung, C.
Janosi, R. A.
Meybohm, P.
Simon, P.
Utzolino, S.
Rahmel, T.
Barth, E.
Jung, C.
Schuster, M.
Aidoni, Z.
Aloizos, S.
Tasioudis, P.
Lampiri, K.
Zisopoulou, V.
Ravani, I.
Pagaki, E.
Antoniou, A.
Katsoulas, T. A.
Kounougeri, A.
Marinakis, G.
Tsimpoukas, F.
Spyropoulou, A.
Zygoulis, P.
Kyparissi, A.
Gupta, M.
Gurjar, M.
Maji, I. M.
Hayes, I.
Marsh, B.
Kelly, Y.
Westbrook, A.
Fitzpatrick, G.
Maheshwari, D.
Motherway, C.
Negri, G.
Spadaro, S.
Nattino, G.
Pedeferri, M.
Boscolo, A.
Rossi, S.
Calicchio, G.
Cubattoli, L.
Di Lascio, G.
Barbagallo, M.
Berruto, F.
Codazzi, D.
Bottazzi, A.
Fumagalli, P.
Negro, G.
Lupi, G.
Savelli, F.
Vulcano, G. A.
Fumagalli, R.
Marudi, A.
Lefons, U.
Lembo, R.
Babini, M.
Paggioro, A.
Parrini, V.
Zaccaria, M.
Clementi, S.
Gigliuto, C.
Facondini, F.
Pastorini, S.
Munaron, S.
Calamai, I.
Bocchi, A.
Adorni, A.
Bocci, M. G.
Cortegiani, A.
Casalicchio, T.
Mellea, S.
Graziani, E.
Barattini, M.
Brizio, E.
Rossi, M.
Hahn, M.
Flaatten, H.
Kemmerer, N.
Strietzel, H. F.
Dybwik, K.
Legernaes, T.
Klepstad, P.
Olaussen, E. B.
Olsen, K. I.
Brresen, O. M.
Bjorsvik, G.
Andersen, F. H.
Maini, S.
Fehrle, L.
Czuczwar, M.
Krawczyk, P.
Ziętkiewicz, M.
Nowak, Ł. R.
Kotfis, K.
Cwyl, K.
Gajdosz, R.
Biernawska, J.
Bohatyrewicz, R.
Gawda, R.
Grudzień, P.
Nasiłowski, P.
Popek, N.
Cyrankiewicz, W.
Wawrzyniak, K.
Wnuk, M.
Maciejewski, D.
Studzińska, D.
Żukowski, M.
Bernas, S.
Piechota, M.
Szczeklik, W.
Nowak-Kózka, I.
Fronczek, J.
Serwa, M.
Machała, W.
Stefaniak, J.
Wujtewicz, M.
Maciejewski, P.
Szymkowiak, M.
Adamik, B.
Polok, K.
Górka, J.
Catorze, N.
Branco, M. C.
Barros, N.
Barros, I.
Krystopchuk, A.
Honrado, T.
Sousa, C.
Munoz, F.
Rebelo, M.
Gomes, R.
Nunes, J.
Dias, C.
Fernandes, A. M.
Petrisor, C.
Constantin, B.
Belskiy, V.
Boskholov, B.
Rodriguez, E.
Aguilar, G.
Masdeu, G.
Jaimes, M. I.
Mira, A. P.
Bodi, M. A.
Mendoza, J. A. B.
López-Cuenca, S.
Guzman, M. H.
Rico-Feijoo, J.
Ibarz, M.
Alvarez, J. Trenado
Kawati, R.
Sivik, J.
Nauska, J.
Smole, D.
Parenmark, F.
Lyrén, J.
Rockstroh, K.
Rydén, S.
Spångfors, M.
Strinnholm, M.
Walther, S.
De Geer, L.
Nordlund, P.
Pålsson, S.
Zetterquist, H.
Nilsson, A.
Thiringer, K.
Jungner, M.
Bark, B.
Nordling, B.
Sköld, H.
Brorsson, C.
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Berkius, J.
Holmström, J.
van Dijk, I.
van Lelyveld-Haas, L. E. M.
Jansen, T.
Nooteboom, F.
van der Voort, P. H. J.
de Lange, D.
Dieperink, W.
de Waard, M. C.
de Smet, A. G. E.
Bormans, L.
Dormans, T.
Dempsey, G.
Mathew, S. J.
Raj, A. S.
Grecu, I.
Cupitt, J.
Lawton, T.
Clark, R.
Popescu, M.
Spittle, N.
Faulkner, M.
Cowton, A.
Williams, P.
Elloway, E.
Reay, M.
Chukkambotla, S.
Kumar, R.
Al-Subaie, N.
Kent, L.
Tamm, T.
Kajtor, I.
Burns, K.
Pugh, R.
Ostermann, M.
Kam, E.
Bowyer, H.
Smith, N.
Templeton, M.
Henning, J.
Goffin, K.
Kapoor, R.
Laha, S.
Chilton, P.
Khaliq, W.
Crayford, A.
Coetzee, S.
Tait, M.
Stoker, W.
Gimenez, M.
Pope, A.
Camsooksai, J.
Pogson, D.
Quigley, K.
Ritzema, J.
Hormis, A.
Boulanger, C.
Balasubramaniam, M.
Vamplew, L.
Burt, K.
Martin, D.
Grecu, I.
Craig, J.
Prowle, J.
Doyle, N.
Shelton, J.
Scott, C.
Donnison, P.
Shelton, S.
Frey, C.
Ryan, C.
Spray, D.
Ryan, C.
Barnes, V.
Barnes, K.
Ridgway, S.
Saha, R.
Kent, L.
Clark, T.
Wood, J.
Bolger, C.
Bassford, C.
Cowton, A.
Lewandowski, J.
Zhao, X.
Humphreys, S.
Dowling, S.
Richardson, N.
Burtenshaw, A.
Stevenson, C.
Wilcock, D.
Nalapko, Y.
,
Joannidis, M.
Eller, P.
Helbok, R.
Schmutz, R.
Nollet, J.
de Neve, N.
De Buysscher, P.
Oeyen, S.
Swinnen, W.
Mikačić, M.
Bastiansen, A.
Husted, A.
Dahle, B. E. S.
Cramer, C.
Sølling, C.
Ørsnes, D.
Thomsen, J. Edelberg
Pedersen, J. J.
Enevoldsen, M. Hummelmose
Elkmann, T.
Kubisz-Pudelko, A.
Pope, A.
Collins, A.
Raj, A. S.
Boulanger, C.
Frey, C.
Hart, C.
Bolger, C.
Spray, D.
Randell, G.
Filipe, H.
Welters, I. D.
Grecu, I.
Evans, J.
Cupitt, J.
Lord, J.
Henning, J.
Jones, J.
Ball, J.
North, J.
Salaunkey, K.
De Gordoa, L. Ortiz-Ruiz
Bell, L.
Balasubramaniam, M.
Vizcaychipi, M.
Faulkner, M.
Mupudzi, M.
Lea-Hagerty, M.
Reay, M.
Spivey, M.
Love, N.
Spittle, N.
White, N.
Williams, P.
Morgan, P.
Wakefield, P.
Savine, R.
Jacob, R.
Innes, R.
Kapoor, R.
Humphreys, S.
Rose, S.
Dowling, S.
Leaver, S.
Mane, T.
Lawton, T.
Ogbeide, V.
Khaliq, W.
Baird, Y.
Romen, A.
Galbois, A.
Guidet, B.
Vinsonneau, C.
Charron, C.
Thevenin, D.
Guerot, E.
Besch, G.
Savary, G.
Mentec, H.
Chagnon, J. L.
Rigaud, J. P.
Quenot, J. P.
Castaneray, J.
Rosman, J.
Maizel, J.
Tiercelet, K.
Vettoretti, L.
Hovaere, M. M.
Messika, M.
Djibré, M.
Rolin, N.
Burtin, P.
Garcon, P.
Nseir, S.
Valette, X.
Rabe, C.
Barth, E.
Ebelt, H.
Fuest, K.
Franz, M.
Horacek, M.
Schuster, M.
Meybohm, P.
Bruno, R. Romano
Allgäuer, S.
Dubler, S.
Schaller, S. J.
Schering, S.
Steiner, S.
Dieck, T.
Rahmel, T.
Graf, T.
Koutsikou, A.
Vakalos, A.
Raitsiou, B.
Flioni, E. N.
Neou, E.
Tsimpoukas, F.
Papathanakos, G.
Marinakis, G.
Koutsodimitropoulos, I.
Aikaterini, K.
Rovina, N.
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Polychronis, T.
Zidianakis, V.
Konstantinia, V.
Aidoni, Z.
Marsh, B.
Motherway, C.
Read, C.
Martin-Loeches, I.
Cracchiolo, A. Neville
Morigi, A.
Calamai, I.
Brusa, S.
Elhadi, A.
Tarek, A.
Khaled, A.
Ahmed, H.
Belkhair, W. Ali
Cornet, A. D.
Gommers, D.
de Lange, D.
van Boven, E.
Haringman, J.
Haas, L.
van den Berg, L.
Hoiting, O.
de Jager, P.
Gerritsen, R. T.
Dormans, T.
Dieperink, W.
Breidablik, A.
Slapgard, A.
Rime, A. K.
Jannestad, B.
Sjøbøe, B.
Rice, E.
Andersen, F. H.
Strietzel, H. F.
Jensen, J. P.
Langørgen, J.
Tøien, K.
Strand, K.
Hahn, M.
Klepstad, P.
Biernacka, A.
Kluzik, A.
Kudlinski, B.
Maciejewski, D.
Studzińska, D.
Hymczak, H.
Stefaniak, J.
Solek-Pastuszka, J.
Zorska, J.
Cwyl, K.
Krzych, Ł. J.
Zukowski, M.
Lipińska-Gediga, M.
Pietruszko, M.
Piechota, M.
Serwa, M.
Czuczwar, M.
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Kozera, N.
Nasiłowski, P.
Sendur, P.
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Carvalho, J. T.
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Catorze, N.
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Lores, A.
Mira, A. P.
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Perez-Torres, D.
Maseda, E.
Rodriguez, E.
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Eixarch, G.
Gomà, G.
Aguilar, G.
Velasco, G. Navarro
Jaimes, M. Irazábal
Villamayor, M. Ibarz
Fernández, N. Llamas
Cubero, P. Jimeno
López-Cuenca, S.
Tomasa, T.
Sjöqvist, A.
Brorsson, C.
Schiöler, F.
Westberg, H.
Nauska, J.
Sivik, J.
Berkius, J.
Thiringer, K. Kleiven
De Geer, L.
Walther, S.
Boroli, F.
Schefold, J. C.
Hergafi, L.
Eckert, P.
Yıldız, I.
Yovenko, I.
Nalapko, Y.
Pugh, R.
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Clinical trials referenced in this document:
nct03134807 at ClinicalTrials.govnct03370692 at ClinicalTrials.govDocuments that mention this clinical trial
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https://doi.org/10.1136/bmjopen-2020-046909
Documents that mention this clinical trial
Contribution of information about acute and geriatric characteristics to decisions about life-sustaining treatment for old patients in intensive care
https://doi.org/10.1186/s12911-022-02094-z
The association of premorbid conditions with 6-month mortality in acutely admitted ICU patients over 80 years
https://doi.org/10.1186/s13613-024-01246-w
Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study
https://doi.org/10.1186/s13054-021-03632-3
The role of clinical phenotypes in decisions to limit life-sustaining treatment for very old patients in the ICU
https://doi.org/10.1186/s13613-023-01136-7
Provision of critical care for the elderly in Europe: a retrospective comparison of national healthcare frameworks in intensive care units
https://doi.org/10.1136/bmjopen-2020-046909
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Article History
Received: 25 April 2021
Accepted: 6 June 2021
First Online: 1 July 2021
Declarations
:
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Each country had a national coordinator responsible for application for national or regional ethical and regulatory study approval. Institutional research ethic board approval was obtained from each study site. Some countries were allowed to recruit patients without prior written informed consent, while others had to collect informed consent from patient or their legal representative.
: Not applicable.
: Joerg C. Schefold declares that the Dept. of Intensive Care Medicine Bern has/had research and/or development/consulting contracts with (full disclosure): Orion Corporation, Abbott Nutrition International, B. Braun Medical AG, CSEM SA, Edwards Lifesciences Services GmbH/SA, Kenta Biotech Ltd, Maquet Critical Care AB, Omnicare Clinical Research AG, and Nestlé. Educational grants were received from Fresenius Kabi; GSK; MSD; Lilly; Baxter; Astellas; AstraZeneca; B. Braun Medical AG, CSL Behring, Maquet, Novartis, Covidien, Nycomed, Pierre Fabre Pharma (Roba Pharma); Pfizer, Orion Pharma. The money went into departmental funds. No personal financial gain applies. All other authors do not have any conflict of interest to declare related to this manuscript.
