Vanhorebeek, Ilse https://orcid.org/0000-0002-5261-5192
Umman Serin, Nazlı https://orcid.org/0000-0001-8215-8909
Güiza, Fabian https://orcid.org/0000-0001-7026-0957
Mebis, Liese https://orcid.org/0000-0002-6941-3044
Verbruggen, Sascha C. A. T. https://orcid.org/0000-0003-4866-9865
Joosten, Koen F. M. https://orcid.org/0000-0002-0504-2475
Van den Berghe, Greet https://orcid.org/0000-0002-5320-1362
Gunst, Jan https://orcid.org/0000-0003-2470-6393
Funding for this research was provided by:
Methusalem Program of the Flemish government (METH14/06)
Methusalem Program of the Flemish government (METH14/06)
Sophia Research Foundation (SSWO grant)
Stichting Agis Zorginnovatie
Erasmus Trustfonds
European Society for Clinical Nutrition and Metabolism (Research Grant)
FP7 Ideas: European Research Council (AdG-2012-321670)
H2020 European Research Council (AdG-2017-785809)
HORIZON EUROPE European Research Council (AdG-2023-101133276)
Institute for Science and Technology, Flanders, Belgium (IWT-TBM150181 and IWT-TBM110685)
Research Foundation-Flanders (1842724N and G029525N)
KU Leuven (STG/23/032)
Article History
Received: 4 November 2025
Accepted: 12 January 2026
First Online: 12 February 2026
Declarations
:
: The participating sites’ institutional review boards approved the original and follow-up studies (Ethical Committee Research UZ/KU Leuven: ML8052; Medische Ethische Toetsingscommissie Erasmus MC: NL49708.078; Ethical Committee Stollery’s Children Hospital: Pro00038098), which were performed in accordance with the 1964 Declaration of Helsinki and its amendments. Written informed consent was acquired from parents or legal guardians.
: Not applicable.
: The authors declare no competing interests.