Zhang, Rui
Xu, Jing
Wu, Jingyi
Tan, Ruoming
He, Huaiwu
Long, Yun
Hong, Donghuang
Wu, Dansen
Qu, Hongping
Zhao, Zhanqi
Liu, Jialin
Funding for this research was provided by:
Shanghai Natural Science Foundation Project (23ZR143980)
Shanghai Municipal Health Commission (20224Y0029)
Article History
Received: 9 April 2026
Accepted: 18 May 2026
First Online: 31 May 2026
Declarations
:
: No animal studies are presented in this manuscript. No potentially identifiable human images or data are presented in this study. The study was approved by the institutional ethics committees of all centers (Ruijin IRB No. [2025030], Fujian Provincial IRB No. [K202502002], Peking Union IRB No. [SK1859]). Written informed consent was obtained from all participants or their legal representatives prior to inclusion. The trial was registered at ClinicalTrials.gov (Identifier: NCT06876792; registered on March 10, 2025).
: In accordance with legislation, written informed consent was obtained from the patient. Patients who were unable to provide consent prior to randomization due to orotracheal intubation or other medical conditions were informed as soon as conditions permitted.
: The authors declare no competing interests.