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Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer

Crossref DOI link: https://doi.org/10.1186/s13058-018-0983-1

Published Online: 2018-06-08

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ribas, Ricardo

Pancholi, Sunil

Rani, Aradhana

Schuster, Eugene

Guest, Stephanie K.

Nikitorowicz-Buniak, Joanna

Simigdala, Nikiana

Thornhill, Allan

Avogadri-Connors, Francesca

Cutler, Richard E. Jr

Lalani, Alshad S.

Dowsett, Mitch

Johnston, Stephen R.

Martin, Lesley-Ann https://orcid.org/0000-0002-7606-4161
Funding

Funding for this research was provided by:

Breast Cancer Now (CTR-Q3, CTR-Q3)

Puma Biotechnology

Arthur Foundation

Arthur Foundation

Royal Marsden NHS Foundation Trust

Royal Marsden NHS Foundation Trust
License Information

Text and Data Mining valid from 2018-06-08
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Article History

Received: 22 January 2018

Accepted: 10 May 2018

First Online: 8 June 2018

Ethics approval and consent to participate

: In-vivo studies were carried out in accordance with Home Office guidelines and approved by the Institute of Cancer Research Ethics Committee.

: All authors approved the final version of this manuscript.

: L-AM and SRJ receive academic funding from PUMA Biotechnology. FA-C, ASL, and REC are employees of PUMA Biotechnology. The remaining authors declare that they have no competing interests.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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