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Article History

Received: 13 September 2024

Accepted: 27 February 2025

First Online: 11 March 2025

Declarations

:

: The project was approved by the Institutional Review Boards of Kaiser Permanente and of the Albert Einstein College of Medicine, both of which granted the study a waiver of informed consent. The work reported here did not involve any direct contact with study subjects– rather, it involved analysis of data and tissue collected previously for clinical reasons.

: Not applicable.

: A case-control study of cancer risk in benign breast disease using AI to predict cellular senescence from biopsy images shows that women with increased senescence have elevated risk of future cancer development.

: IH, MP, and MSK have filed a provisional patent related to risk prediction methods. All other authors declare no competing interests.