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Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

Crossref DOI link: https://doi.org/10.1186/s13059-017-1362-4

Published Online: 2017-12-20

Published Print: 2017-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Müller, Sören

Kohanbash, Gary

Liu, S. John

Alvarado, Beatriz

Carrera, Diego

Bhaduri, Aparna

Watchmaker, Payal B.

Yagnik, Garima

Di Lullo, Elizabeth

Malatesta, Martina

Amankulor, Nduka M.

Kriegstein, Arnold R.

Lim, Daniel A.

Aghi, Manish

Okada, Hideho

Diaz, Aaron https://orcid.org/0000-0001-9059-9501
Funding

Funding for this research was provided by:

The Shurl and Kay Curci Foundation

National Institutes of Health (P50-CA097257-13:7017, P30-CA82103-18)

The Dabbiere Family

The Cancer League
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Text and Data Mining valid from 2017-12-01

Version of Record valid from 2017-12-20
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Article History

Received: 24 July 2017

Accepted: 17 November 2017

First Online: 20 December 2017

Ethics approval and consent to participate

: Study protocols were approved by the UCSF Institutional Review Board (IRB# 11-06160) and the University of Pittsburgh Institutional Review Board (IRB# PRO13070533). All clinical samples were analyzed in a de-identified fashion. All experiments were carried out in conformity to the principles set out in the WMA Declaration of Helsinki as well as the Department of Health and Human Services Belmont Report. Informed written consent was provided by all patients.

: The authors declare that they have no competing interests.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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