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Article History

Received: 19 July 2017

Accepted: 1 May 2018

First Online: 20 June 2018

Ethics approval and consent to participate

: Ethical approvals were obtained at each study site and informed consent was obtained from all participants. All studies involving human volunteers or human material have been performed in accordance with the Declaration of Helsinki and have been approved by an appropriate ethics committee. <i>Carbohydrate Overfeeding in Healthy Human Adults</i>: This study was approved by Cambridge South Research Ethics Service Committee (Ref. no.: 14/EE/0054). <i>Murine dietary intervention study:</i> All procedures involving mice were performed by a licence holder in accordance with the UK Home Office Animals (Scientific Procedures) Act 1986. <i>The University of Cambridge Animal Welfare and Ethical Review Committee</i>. <i>Fenland and NSHD cohorts:</i> Ethical approvals were obtained at each study site, and informed consent was obtained from all participants.

: The authors have declared that no conflict of interest exists. In 2015, the Scientific Advisory Committee on Nutrition (SACN), UK established a working group to examine the evidence linking dietary fats and health outcomes. JLG is a member of that group. All of the opinions in this manuscript are those of the authors and should not be taken as a reflection of the views of SACN’s working group on fats.

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