Madissoon, E.
Wilbrey-Clark, A.
Miragaia, R. J.
Saeb-Parsy, K.
Mahbubani, K. T.
Georgakopoulos, N.
Harding, P.
Polanski, K.
Huang, N.
Nowicki-Osuch, K.
Fitzgerald, R. C.
Loudon, K. W.
Ferdinand, J. R.
Clatworthy, M. R.
Tsingene, A.
van Dongen, S.
Dabrowska, M.
Patel, M.
Stubbington, M. J. T.
Teichmann, S. A.
Stegle, O.
Meyer, K. B. http://orcid.org/0000-0001-5906-1498
Article History
Received: 9 August 2019
Accepted: 28 November 2019
First Online: 31 December 2019
Ethics approval and consent to participate
: Tissue samples were obtained from the Cambridge Biorepository for Translational Medicine (CBTM [CitationRef removed];) with informed consent from the donor families and approval from the NRES Committee of East of England—Cambridge South (15/EE/0152). This consent includes generation of open-access genetic sequencing data and publication in open access journals in line with Wellcome Trust policy. CBTM operates in accordance with UK Human Tissue Authority guidelines (HTA [CitationRef removed];). All experimental methods comply with the Helsinki Declaration.
: All samples were provided as linked-anonymized, with the linkage key held by the clinician. Consent was obtained as part of the Research Ethics Committee (REC) approval.
: MJTS has been employed by 10x Genomics since April 2018; this employment had no bearing on this work. RJM has been employed by MedImmune/AstraZeneca since October 2018; this employment had no bearing on this work. The other authors declare that they have no competing interests.