McCartney, Daniel L. https://orcid.org/0000-0003-3242-0360
Hillary, Robert F.
Conole, Eleanor L. S.
Banos, Daniel Trejo
Gadd, Danni A.
Walker, Rosie M.
Nangle, Cliff
Flaig, Robin
Campbell, Archie
Murray, Alison D.
Maniega, Susana Muñoz
Valdés-Hernández, María del C.
Harris, Mathew A.
Bastin, Mark E.
Wardlaw, Joanna M.
Harris, Sarah E.
Porteous, David J.
Tucker-Drob, Elliot M.
McIntosh, Andrew M.
Evans, Kathryn L.
Deary, Ian J.
Cox, Simon R.
Robinson, Matthew R.
Marioni, Riccardo E.
Funding for this research was provided by:
wellcome trust (104036/Z/14/Z, 108890/Z/15/Z, 108890/Z/15/Z, 108890/Z/15/Z)
medical research council ([G0701120], [G1001245], [MR/M013111/1] and [MR/R024065/1])
horizon 2020 (PHC.03.15, project No 666881)
biotechnology and biological sciences research council (BB/F019394/1)
national institutes of health (R01AG05462802S1, R01AG054628, R01MH120219, R01HD083613, P2CHD042849 and P30AG066614, R01AG054628)
age uk (R01AG054628)
alzheimer’s research uk (ARUK/PG2017B/10, ARUK/PG2017B/10)
mrs gladys row fogo charitable trust (BROD.FID3668413)
Article History
Received: 26 July 2021
Accepted: 29 December 2021
First Online: 17 January 2022
Declarations
:
: All components of GS received ethical approval from the NHS Tayside Committee on Medical Research Ethics (REC Reference Number: 05/S1401/89). GS has also been granted Research Tissue Bank status by the East of Scotland Research Ethics Service (REC Reference Number: 20-ES-0021), providing generic ethical approval for a wide range of uses within medical research.Ethical approval for the LBC1921 and LBC1936 studies was obtained from the Multi-Centre Research Ethics Committee for Scotland (MREC/01/0/56) and the Lothian Research Ethics committee (LREC/1998/4/183; LREC/2003/2/29). In both studies, all participants provided written informed consent. These studies were performed in accordance with the Helsinki declaration.
: Not applicable
: R.E.M has received a speaker fee from Illumina and is an advisor to the Epigenetic Clock Development Foundation. A.M.M has previously received speaker fees from Janssen and Illumina and research funding from The Sackler Trust. All other authors declare no competing interests.