Gong, Xiaoli
He, Wei
Jin, Wan
Ma, Hongwei
Wang, Gang
Li, Jiaxin
Xiao, Yu
Zhao, Yangyu
Chen, Qiong
Guo, Huanhuan
Yang, Jiexia
Qi, Yiming
Dong, Wei
Fu, Meng
Li, Xiaojuan
Liu, Jiusi
Liu, Xinghui
Yin, Aihua
Zhang, Yi https://orcid.org/0000-0001-5388-1276
Wei, Yuan
Funding for this research was provided by:
Key Technologies Research and Development Program (2023YFC2705900)
National Natural Science Foundation of China (82171661)
Article History
Received: 18 August 2022
Accepted: 30 April 2024
First Online: 7 May 2024
Declarations
:
: The study protocol was approved by Peking University Third Hospital Medical Science Research Ethics Committee (approval number: (2020)YiLun(310–02)), Peking University Institutional Review Board (approval number: IRB0001052-16009), Institutional Review Board of Guangdong Woman and Children’s Hospital (approval number: YiLun [201701044]), Ethics Committee of the West China Second Hospital of Sichuan University (approval number: YiXueKeYan2020(064)) and Institutional Ethics Committee of Zhongnan Hospital of Wuhan University (approval number: 2015029 and 2020102). Informed consent was obtained from the donors and their guardians.
: W.J., Q.C., H.H.G., X.J.L, J.S.L, and Y.Z. are current or former employees of Euler Technology, Beijing, China. Provisional patents were filed for the single-stranded NGS library preparation method Tequila 7N (WO 2020/073748) and the method for using cell-free DNA methylation pattern to predict placenta development status and pregnancy outcome (202010084924.X) by Euler Technology. These patents do not limit the use of the methods or reproducibility of the results. The other authors declare that they have no competing interests.