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Authors
Safina, Ksenia R.
Salik, Basit
Kotliar, Dylan
Curtis, Michelle
Good, Jonathan D.
Weng, Chen
David, Shawn
Raychaudhuri, Soumya
Kreso, Antonia
Trowbridge, Jennifer J.
Sankaran, Vijay G.
van Galen, Peter
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Funding
Funding for this research was provided by:
National Institutes of Health (1K99HG013991-01)
National Institutes of Health (R01DK118072, R01AG069010, U01AG077925)
National Institutes of Health (R01DK103794, R01HL146500, R01CA265726, R01CA292941, R33CA278393)
National Institutes of Health (R33CA278393 , U01AG077925)
Mark Foundation for Cancer Research
Blood Cancer United
Edward P. Evans Foundation
Vera and Joseph Dresner Foundation
Howard Hughes Medical Institute
Mathers Foundation
Starr Cancer Consortium
Ludwig Center at Harvard
MPN Research Foundation
Research Scholar Grant from the American Cancer Society (RSG-24-1318769-01-CDP)
Brigham Research Institute
Hevolution/American Federation for Aging Research (New Investigator Award in Aging Biology and Geroscience Research)
Krantz Family Center for Cancer Research
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Article History
Received: 12 August 2025
Accepted: 5 January 2026
First Online: 16 January 2026
Declarations
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: Sternum bone marrow samples from the Safina dataset and for flow cytometry analysis were collected under an excess sample banking and sequencing protocol approved by the Mass General Brigham Institutional Review Board (IRB protocol 2020P004103) and conducted in accordance with the Declaration of Helsinki. Participants provided written informed consent prior to inclusion in the study, including consent for publication of de-identified data. Additional datasets were obtained from public repositories.
: Not applicable.
: The authors declare no competing interests.
