Hess, Anja https://orcid.org/0000-0001-6634-9502
Kovacsovics, Alexander
Bachinger, Fabian https://orcid.org/0009-0003-9889-3811
Vallier, Ludovic https://orcid.org/0000-0002-3848-2602
Kretzmer, Helene https://orcid.org/0000-0002-0723-4980
Meissner, Alexander https://orcid.org/0000-0001-8646-7469
Funding for this research was provided by:
Max-Planck-Gesellschaft
European Research Council (101098178)
Max Planck Institute for Molecular Genetics
Article History
Received: 13 August 2025
Accepted: 3 February 2026
First Online: 17 February 2026
Declarations
:
: No new human cell lines were derived (not applicable).
: This manuscript does not contain data from any individual person (not applicable).
: A.M. is inventor on a patent related to hypermethylated CGI targets in cancer and co-founder as well as scientific advisor of Harbinger Health. LV is a founder and shares holder of DefiniGEN and Bilitech. LV is a shares holder in Bit.bio. FB’s work is supported by Bit.bio. The other authors declare no conflict.