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Authors
Gao, William
Hu, Peng
Wick, Brittney
Qiu, Qi
Zhang, Hongjie
Li, Ying
Kang, Xiangjin
Bedi, Kenneth
Haeussler, Maximilian
Sasaki, Kotaro
Margulies, Kenneth
Wu, Hao
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Funding
Funding for this research was provided by:
National Human Genome Research Institute (T32HG000046-26)
National Human Genome Research Institute (U24HG002371)
National Human Genome Research Institute (U01-HG012047)
National Institute of General Medical Sciences (T32GM148377)
National Institute of Mental Health (RF1MH132662)
California Institute for Regenerative Medicine (DISC0-14514)
National Heart, Lung, and Blood Institute (DP2-HL142044)
Fondation Leducq (20CVD02)
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Article History
Received: 20 October 2025
Accepted: 24 March 2026
First Online: 6 April 2026
Declarations
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: For all new snRNA-seq and snATAC-seq datasets generated in this study, we have received approval through the Penn Heart Tissue Biobank, which has been approved by the Penn IRB (#848421) since 2005. For fetal donors, the IRB number is 832470. Written informed consent for research use of donated tissue was obtained from next of kin in all cases. The consent forms explicitly provide permission to generate and disseminate genomic data from de-identified subjects. The experimental methods used in this work comply with the Helsinki Declaration.
: The authors declare no competing interests.
