Pan, Feifei
Qiu, Yuqing
Huang, Zhuojie
Zheng, Yanqin
Chen, Yun
Song, Yiming
Chen, Zhe-Sheng
Guo, Lirong
Wang, Jingyao
Liu, Xiaojie
Tao, Zixin
Liu, Yaqiong
Xuan, Xingcui
Gong, Kunxiang
Shi, Kun
Funding for this research was provided by:
National Natural Science Foundation of China (82404926)
National Natural Science Foundation of China (82072859)
Basic and Applied Basic Research Foundation of Guangdong Province (2025A1515011310)
Basic and Applied Basic Research Foundation of Guangdong Province (2022A1515220127)
Article History
Received: 1 October 2025
Accepted: 5 December 2025
First Online: 15 December 2025
Declarations
:
: Ethics approval and consent to participate in the acquisition and use of human specimens were in concordance with the International Ethical Guidelines for Research Involving Human Subjects, as stated in the Helsinki Declaration, and were approved by the Medical Ethics Committee of Guangzhou Women and Children’s Medical Center (Approval number: 124B00). The specific information of the patients involved in this study was presented in Additional file 4. The animal experiments were approved by the Guangzhou Women and Children’s Medical Center Animal Welfare and Ethics Committee (Approval number: RSDW202301427) and were conducted in accordance with the NIH Guidelines for the Care and Use of Laboratory Animals.
: Not applicable.
: Not applicable.
: The authors declare no competing interests.