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Revealing FPR1 as a potential pathogenic biomarker for aortic dissection based on Mendelian randomization, single-cell transcriptome and clinical data analysis

Crossref DOI link: https://doi.org/10.1186/s13062-026-00732-4

Published Online: 2026-01-31

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Liu, Zihao

Ran, Haoyu

Tang, Yuquan

Li, Lei

Gao, Zhenyu

Li, Zhixin

Xie, Yucheng

Zeng, Qinglian

Yu, Fengxu
Funding

Funding for this research was provided by:

2022 Sichuan Province Science and Technology Plan joint innovation project (No.: 2022YFS0610 and No.: 2022YFS0617)

Key Laboratory of Medical Electrophysiology Open Fund research project (No.: KeyME- 2023-01)
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Text and Data Mining valid from 2026-01-31

Version of Record valid from 2026-03-02
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Article History

Received: 21 November 2025

Accepted: 24 January 2026

First Online: 31 January 2026

Declarations

:

: The present study was approved by the Ethics Committee of the Affiliated Hospital of Southwest Medical University, and all experiments were performed according to the principles of the Declaration of Helsinki. All animal experiments were conducted under specific pathogen-free barrier conditions according to institutional guidelines and were approved by the Animal Experimentation Ethics Committee of Southwest Medical University. Clinical trial number: not applicable.

: Not applicable.

: The authors declare no competing interests.

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