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Clayton, Gemma L.

Smith, Isabelle L.

Higgins, Julian P. T.

Mihaylova, Borislava

Thorpe, Benjamin

Cicero, Robert

Lokuge, Kusal

Forman, Julia R.

Tierney, Jayne F.

White, Ian R.

Sharples, Linda D.

Jones, Hayley E.

Funding for this research was provided by:

Medical Research Council (GB) Hubs for Trials Methodology Research (HTMR) network (Bristol) (K025643/1)

Medical Research Council Hubs for Trials Methodology Research (HTMR) network (London) (G0800814)

Medical Research Council (GB) career development award in biostatistics (M014533/1)

Medical Research Council (U105260558)

MRC Population Health Research Unit (MRC-E270)

MRC PhD Studentship (HTMR Q10 (see funding document attached))

Nuffield Department of Population Health Studentship, University of Oxford (Studentship (see funding document attached))