Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (KL 2918/2-1)
Received: 5 October 2018
Accepted: 14 January 2019
First Online: 4 February 2019
Ethics approval and consent to participate
: This clinical trial will be undertaken strictly according to the protocol and GCP regulations. The study protocol was approved by the Institutional Review Board (IRB) of the University Hospital Essen (18–8288-BO). All participants will receive oral and written information about the trial and must give their written informed consent before enrolment. Participants are free to withdraw at any time.
: Not applicable.
: The authors declare that they have no competing interests.
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