Funding for this research was provided by:
Tsumura & Co.
Received: 29 March 2018
Accepted: 16 January 2019
First Online: 8 February 2019
Ethics approval and consent to participate
: Informed written consent was obtained from all participants. The Ethical Review Board, National Cancer Center Japan approved the study protocol.
: Not applicable.
: Dr. Shimizu has received a Grant-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science (15K08832), from Research for Promotion of Cancer Control Programmes (H27-political-general), and from Tsumura & Co. Dr. Sadahiro has received Sasakawa Foundation Butterfield awards (B108) and a grant from SGH Foundation. Dr. Matsuoka has received a Grant-in-Aid for Scientific Research (B) from the Japan Society for the Promotion of Science (17H04253), an intramural research grant for Neurological and Psychiatric Disorders from the National Center of Neurology and Psychiatry Japan (27-3-2), and a grant from SENSHIN Medical Research Foundation, and has also received speaker’s honoraria from Eli Lilly Japan K.K., Morinaga Milk Industry Co., Ltd., and Takeda Pharmaceutical Company Ltd. Dr. Uchitomi has received Grants from the National Cancer Center Research and Development Fund (27-A-3), Research for Promotion of Cancer Control Programmes (H29-political-general), and Japan Agency for Medical Research and development, AMED. Dr. Yamaguchi received consulting fees from Tsumura & Co.
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