,
Sihvonen, Raine
Kalske, Roope
Englund, Martin
Turkiewicz, Aleksandra
Toivonen, Pirjo
Taimela, Simo
Järvinen, Teppo L. N. https://orcid.org/0000-0003-3713-956X
Funding for this research was provided by:
Sigrid Juséliuksen Säätiö
Article History
Received: 30 July 2019
Accepted: 22 October 2019
First Online: 14 January 2020
Ethics approval and consent to participate
: Central ethical approval was confirmed from the Pirkanmaa Hospital District’s committee of ethics (reference approval no. R06157) and we did not begin recruiting at other centers in the trial until local ethical approval was obtained. Informed consent was obtained from all study participants at trial entry.
: Not applicable.
: All authors have completed the ICMJE uniform disclosure form at and declare no support from any organization for the submitted work; no financial relationships with any organizations that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work.