Document is current

Article History

Received: 8 September 2021

Accepted: 5 February 2022

First Online: 19 February 2022

Declarations

:

: The study has been approved by the IEC of the following sites: Aarhus University (Denmark) (Central Denmark Region Committees on Health Research Ethics, no. 1-10-72-133-19), the Comité d'Ethique hospitalo-facultaire of the Cliniques universitaires Saint-Luc (Belgium), the Ethik-Kommission II der Universität Heidelberg (Germany), and the Comitato Etico Sapienza Universita di Roma (Italy).Written informed consent to participate will be provided by each participant before the start of study assessments or the intervention. These may be requested by contacting sponsor.

: Not applicable.

: OC, FF, CL, AVK, AM, ZN, HP, ASc, ASt, ES, HT, BG, and VW declare they have no conflict of interest. PBF and JVN were employees of Grünenthal when they contributed to the study protocol, and PBF also reports consultancy fees from ConsulTech. IB is an employee of Grünenthal. NBF reports personal fees from Almirall, NeuroPN, Novartis Pharma, and Vertex and has undertaken consultancy work for Aarhus University with remunerated work for Biogen, Merz, and Confo Therapeutics, outside the submitted work. SCC is an employee and shareholder of Eli Lilly and Company. KGP is an employee of Eli Lilly and Company. KS is an employee of ConsulTech. TL is an employee of Teva Pharmaceuticals. JVN was an employee of Grünenthal when he contributed to the protocol and reports personal fees from Medwis-extern GmbH & Co.KG, outside the submitted work. AT reports personal fees from Angelini, Almirall, Grunenthal, and Eliem Therapeutics, outside the submitted work. IFT has received personal fees from Grünenthal, outside the submitted work. IT reports personal fees from royalties on books, personal fees from advisory board for Amgen Neuroscience, personal fees from Consultant to Cannbiorex Life 180, personal fees from honoraria for education talks for Grünenthal, outside the submitted work. JV has received personal fees from Vertex Pharmaceuticals and Embody Orthopaedic, outside the submitted work. JMV is an employee of Welab Barcelona. KV reports personal fees from Bayer Healthcare, Grünenthal, Eli Lilly and Company, and AbbVie, outside the submitted work. RDT reports personal fees from Bayer, Grünenthal, GSK, and Sanofi outside the submitted work. In addition, he has a patent DE 103 31 250.1-35 with royalties paid to MRC Systems. MRC Systems (BP and MG) develop, produce, and market products in the field of QST. MW reports personal fees from Novartis, Alnylam, Amicus, Biogen, Bristol-Myers-Squibb, Pfizer, Bial, and other from Boehringer-Ingelheim Foundation, outside the submitted work. EPZ reports fees from Mundipharma, Novartis, and Grünenthal, outside the submitted work. All authors are partners of the IMI2-PainCare consortium (ExternalRef removed).