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Effectiveness and safety of mesenchymal stem/stromal cell for radiation-induced hyposalivation and xerostomia in previous head and neck cancer patients (MESRIX-III): a study protocol for a single-centre, double-blinded, randomised, placebo-controlled, phase II study

Crossref DOI link: https://doi.org/10.1186/s13063-023-07594-5

Published Online: 2023-09-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jakobsen, Kathrine Kronberg https://orcid.org/0000-0003-0336-5411
Carlander, Amanda-Louise Fenger

Grønhøj, Christian

Todsen, Tobias

Melchiors, Jacob

Paaske, Natasja

Madsen, Anne Kathrine Østergaard

Kastrup, Jens

Ekblond, Annette

Haack-Sørensen, Mandana

Farhadi, Mohammad

Maare, Christian

Friborg, Jeppe

Lynggard, Charlotte Duch

von Buchwald, Christian
Funding

Funding for this research was provided by:

Rigshospitalet (R198-A9014)

Candys Foundation (No grant number)

Royal Library, Copenhagen University Library
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Text and Data Mining valid from 2023-09-01

Version of Record valid from 2023-09-01
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Article History

Received: 24 May 2023

Accepted: 17 August 2023

First Online: 1 September 2023

Declarations

:

: The authors C.D.L., C.G., and C.V.B. declare the following competing interests: Rigshospitalet and the University of Copenhagen have a pending patent application entitled “Stem cell therapy for salivary gland dysfunction” published as WO 2020/165405 A1, with K.K.J, C.D.L., C.G., and C.V.B. as the inventors. The authors A.E., M.H.S. and J.K. declare the following competing interests: A.E., M.H.S. and J.K. are inventors of the patent “Stem cell therapy based on adipose-derived stem cells” (Publication WO 2017-068140). All authors met the ICMJE authorship criteria. No honoraria or payments were made for authorship. The remaining authors declare no competing interests.

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