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Article History

Received: 9 April 2024

Accepted: 4 July 2024

First Online: 13 July 2024

Declarations

:

: The study has been reviewed and received ethical approval by the Medical Sciences Interdivisional Research Ethics Committee of the University of Oxford (R89540/RE001). Participants consent to be involved in internal and external research and for their data to be used for academic research purposes by accepting the Second Nature Terms & Conditions and Privacy Policy.

: Not applicable—no identifying images or other personal or clinical details of participants are presented here or will be presented in reports of the trial results. The Second Nature Terms & Conditions and Privacy Policy, which outlines consent for publication, are available as supplementary material.

: Second Nature is the industrial partner on GMW’s MRC industrial collaborative awards in science and engineering (iCASE) studentship. DAK and SAJ report being investigators in two publicly funded (NIHR) trial where the weight loss intervention was donated by Nestle Health Science and Oviva to the University of Oxford outside the submitted work. SAJ and JS report being investigators in a trial where Second Nature is delivering the weight loss intervention outside of this work. JS was a member of a Nestle Health Sciences advisory board and was an invited speaker at a Nestle Health Sciences webinar, for which a personal honorarium was received. GP, MH, DE, and MW are employees of Second Nature. No other conflicts of interest are reported.