Document is current

Article History

Received: 19 April 2024

Accepted: 7 April 2025

First Online: 11 June 2025

Declarations

:

: The protocol was already presented to the REB and approved in all sites with references. Copy of the original ethical approval documents is provided as an additional file (Additional file 2).

: A model consent document was distributed to local investigators at each center and is provided as an additional file (Additional file 3).

: AP reports non-financial support from STIMIT AG (Biel, Switzerland) for travel. AP holds stocks in small amounts from BioNTech SE, Taiwan Semiconductor, Sony, Pfizer, Arcutis Biotherapeutics Inc, Sangamo Therapeutics, NIO, Ke Holdings; these holdings have not affected any decisions regarding this trial. SJS received grants from STIMIT AG (Biel, Switzerland) to support this trial. SJS reports grants and non-financial support from Reactive Robotics GmbH (Munich, Germany), ASP GmbH (Attendorn, Germany), STIMIT AG (Biel, Switzerland), ESICM (Geneva, Switzerland), grants, personal fees, and non-financial support from Fresenius Kabi Deutschland GmbH (Bad Homburg, Germany), grants from the Innovations fond of The Federal Joint Committee (G-BA), personal fees from Springer Verlag GmbH (Vienna, Austria) for educational purposes and Advanz Pharma GmbH (Bielefeld, Germany), non-financial support from national and international societies (and their congress organizers) in the field of anesthesiology and intensive care medicine, outside the submitted work. SJS holds stocks in small amounts from Alphabet Inc., Bayer AG, and Siemens AG; these holdings have not affected any decisions regarding his research or this trial.