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Effect of different targeted tidal volumes during high-frequency oscillation with volume-targeted ventilation on cerebral blood flow velocity and cardiac output: study protocol for a randomised crossover study

Crossref DOI link: https://doi.org/10.1186/s13063-025-09179-w

Published Online: 2025-10-22

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kaltsogianni, Ourania

Nanjundappa, Mahesh

Okoye, Grace

Greenough, Anne

Dassios, Theodore https://orcid.org/0000-0001-5258-5301
Funding

Funding for this research was provided by:

King's Medical Research Trust
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Text and Data Mining valid from 2025-10-22

Version of Record valid from 2025-10-22
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Article History

Received: 11 March 2025

Accepted: 29 September 2025

First Online: 22 October 2025

Ethics approval and consent to participate

: This study was reviewed and approved by the Health Research Authority (HRA) and the London Hampstead Research Ethics Committee (Reference 25/LO/0026). The sponsor is King’s College Hospital NHS Foundation Trust.Written informed parental consent is obtained for recruitment to the study.

: N/A.

: The authors declare that they have no competing interests.

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