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Supplemental choline to prevent and treat learning and memory deficits of early-life iron deficiency (The SupCHO Study): study protocol for a randomized, placebo-controlled trial in Ugandan infants with iron deficiency anemia

Crossref DOI link: https://doi.org/10.1186/s13063-025-09246-2

Published Online: 2025-11-19

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Cusick, Sarah E.

Mupere, Ezekiel

Bangirana, Paul

Baluku, Reagan I.

Kroupina, Maria

Cheatham, Carol L.

Wozniak, Jeffrey R.

Georgieff, Michael K.
Funding

Funding for this research was provided by:

Thrasher Research Fund (E.W. "Al" Thrasher Award)

University of Minnesota (MIDB Faculty Award)
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Text and Data Mining valid from 2025-11-19

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Article History

Received: 22 July 2025

Accepted: 19 October 2025

First Online: 19 November 2025

Declarations

:

: University of Minnesota Institutional Review Board # STUDY00022408 version 1 date 6/18/2024; version 1.1 date 7/2/2025Mulago Hospital Research Ethics Committee Date # MHREC 2024-158 version 1 5/5/2024; version 1.1 6/24/2025Uganda National Council of Science and Technology: HS4915ES 11/13/2024Uganda National Drug Authority: CTA 0288/2025Written, informed consent to participate will be obtained from the caretakers of all participants.

: Attached.

: The authors declare that they have no competing interests.

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