Donnelly, Owain
Mesquita, Silvia
Archer, John
Ali, Said M.
Bartonicek, Zikmund
Lugli, Elena B.
Webster, Bonnie L.
Funding for this research was provided by:
Mason Medical Research Trust
London School of Hygiene and Tropical Medicine
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (001)
Natural Environment Research Council (NE/L002485/1)
Coalition for Operational Research on Neglected Tropical Diseases (OPP1190754)
Article History
Received: 25 April 2024
Accepted: 26 June 2024
First Online: 28 July 2024
Declarations
:
: Urine samples were originally collected as part of the Zanzibar Elimination of Schistosomiasis Transmission (ZEST) project, which was implemented from 2011 to 2017 []. Details on how urine samples were collected, screened for <i>S. haematobium</i> infection, and stored have been outlined previously []. ZEST received permission to store and share urine samples from study participants for research purposes and received ethical approval from the Zanzibar Medical Research Ethical Committee (ZAMREC; reference number: ZAMREC 0003/Sept/011); the Swiss Ethikkommission beider Basel (EKBB; reference number: EKBB 236/11); and the Institutional Review Board of the University of Georgia (IRB UGA project number: 2012-10138-0). ZEST was also registered on the International Standard Randomised Controlled Trial Number Register (ISRCTN48837681). Written informed consent from parents or legal guardians of participating children in Zanzibar was obtained for urine collection and storage, including examination for <i>S. haematobium</i> infections with newly developed diagnostic techniques at a later point in time. All study participants were offered praziquantel (40 mg/kg) to treat schistosomiasis free of charge during the ongoing biannual island-wide MDA campaign.
: Not applicable.
: The authors declare that they have no competing interests.