Li, Ya-Nan
Sun, Hang
Ma, Jian
Zhou, Xin-Yuan
Xie, Xiao-Man
Xie, Huan-Huan
Hou, Yan-Han
Dong, Hong-Jie
Zhao, Gui-Hua
Xu, Chao
Li, Hong-Tao
Yin, Kun
Funding for this research was provided by:
Natural Science Foundation of Shandong Province (ZR2022MH197)
Taishan Scholars Project of Shandong Province (tsqn202103186)
Joint Innovation Team for Clinical & Basic Research (202407)
Innovation Project of Shandong Academy of Medical Sciences
Medical and Health Science and Technology Key Program of Shandong Province (202501050649)
Article History
Received: 23 October 2025
Accepted: 4 February 2026
First Online: 26 February 2026
Declarations
:
: All animal experiments were conducted in strict accordance with the International Guiding Principles for Biomedical Research Involving Animals, as issued by the Council for the International Organizations of Medical Sciences (CIOMS), the guidelines established by the International Animal Care and Use Committee of Shandong First Medical University (Approval No. W202402270064), and the Animal Research: Reporting of in Vivo Experiments (ARRIVE) guidelines.
: Not applicable.
: The authors declare no competing interests.