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Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells

Crossref DOI link: https://doi.org/10.1186/s13073-018-0581-y

Published Online: 2018-09-20

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Leung, Cherry S.

Yang, Kevin Y.

Li, Xisheng

Chan, Vicken W.

Ku, Manching

Waldmann, Herman

Hori, Shohei

Tsang, Jason C. H.

Lo, Yuk Ming Dennis

Lui, Kathy O. https://orcid.org/0000-0002-1616-3643
Funding

Funding for this research was provided by:

Research Grants Council, University Grants Committee (04110515, 14111916, C4024-16W, C4026-17WF)

Health and Medical Research Fund (03140346, 04152566)
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Article History

Received: 15 January 2018

Accepted: 7 September 2018

First Online: 20 September 2018

Ethics approval

: All animal procedures were approved by the CUHK Animal Experimentation Ethics Committee and performed in compliance with the <i>Guide for the Care and Use of Laboratory Animals</i> (NIH publication, eighth edition, updated 2011). The use of hESC lines does not require additional ethical approval by our institute.

: N/A

: The authors declare that they have no competing interests.

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