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Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

Crossref DOI link: https://doi.org/10.1186/s13073-019-0613-2

Published Online: 2019-01-31

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Taylor, Kurt

Davey Smith, George

Relton, Caroline L.

Gaunt, Tom R.

Richardson, Tom G.
Funding

Funding for this research was provided by:

British Heart Foundation (SSCM SJ1429)

Medical Research Council (MC_UU_00011/1, MC_UU_00011/4, MC_UU_00011/5)

Health Data Research UK (MR/S003886/1)
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Article History

Received: 5 November 2018

Accepted: 8 January 2019

First Online: 31 January 2019

Ethics approval and consent to participate

: All procedures were ethically approved by the ALSPAC ethics and Law Committee and the Local Research Ethics Committees. Written informed consent was obtained from all participants. We were granted access to ALSPAC data under project B2965 “Evaluating the causal effect of gene expression on cardiovascular function” (04/10/2017). The research was conducted in accordance with the declaration of Helsinki.

: Not applicable

: The authors declare that they have no competing interests.

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