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Article History

Received: 26 June 2019

Accepted: 19 December 2019

First Online: 8 January 2020

Authors’ information

: Additional author information for M. D. S, K. J., C. L., D. L. S (affiliated with the Armed Forces Research Institute of Medical Sciences): Material has been reviewed by the Walter Reed Army Institute of Research. There is no objection to its presentation and/or publication. The opinions or assertions contained herein are the private views of the author and are not to be construed as official or as reflecting true views of the Department of the Army or the Department of Defense. The investigators have adhered to the policies for protection of human subjects as prescribed in AR 70–25.

: <i>P. falciparum</i> isolates for which whole genome sequence data was first reported in this study were collected during field studies in Brazil, Malawi, Mali, Myanmar, and Thailand. All isolates were collected after recruitment, and with written informed consent from the subject or a parent/guardian, and assent obtained from children under 18 years old. Informed consent included the generation of parasite genomic data. The respective field studies were approved by the following institutional review boards (IRBs): Institute of Biomedical Sciences, University of São Paulo (1368/17/CEPSH), for collection in Acre, Brazil; Malawi National Health Sciences Research Committee, and the IRB at the University of Maryland, Baltimore (FWA# 00005976), for collection in Malawi; Comité D’Éthique de la FMPOS (Faculté de Médecine de Pharmacie et d’Odonto-stomatologie), Université des Sciences, des Techniques, et des Technologies de Bamako, Mali, and the IRB at the University of Maryland, Baltimore (HP-00041382), for collection on Mali; Ethics Review Committee of the Department of Medical Research, Myanmar Ministry of Health and Sports, Yangon, Myanmar, and the IRB at the University of Maryland, Baltimore (FWA# 00018816, IRB# 00008835), for collections in Myanmar; Human Subject Protection Branch (HSPB) of the Walter Reed Army Institute of Research, Silver Spring, MD (FWA# 00000015, IRB# 00000794), and Institute for the Development of Human Research Protection (IHRP), Ministry of Public Health, Thailand (FWA# 00017503, IRB# 00006539), for collections in Thailand. This study conforms to the principles established in the Helsinki Declaration.

: Not applicable.

: T.L., B.K.L.S., and S.L.H. are salaried employees of Sanaria Inc., the developer and owner of PfSPZ vaccine, and the supplier of the PfSPZ strains sequenced in this study. In addition, S.L.H. and B.K.L.S. have a financial interest in Sanaria Inc. The remaining authors declare that they have no competing interests.