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Article History

Received: 29 September 2020

Accepted: 30 April 2021

First Online: 17 May 2021

Declarations

:

: This study was approved by the Ethics Committee of the University Hospital of Essen under the reference number 12-5265-BO. Written informed consent was obtained from all participants at enrollment, and specimens were collected using protocols approved by the ethics commission. This research conformed to the principles of the Helsinki Declaration.

: Not applicable.

: C.K. received support for travel expenses from QIAGEN, Hilden, Germany. V.S., S.H., M.S., P.H., and M.S.H are employees at QIAGEN, Hilden, Germany. H.C.K. has received honoraria from Pfizer, Novartis, Roche, Genomic Health, Amgen, AstraZeneca, Riemser, Carl Zeiss Meditec, TEVA, Theraclion, Janssen-Cilag, GSK, LIV Pharma, Onkowissen, and SurgVision. H.C.K. received nonfinancial support from Carl Zeiss Meditec, Novartis, Pfizer, Amgen, Roche, LIV Pharma, Tesaro, Daiichi Sankyo, and Genomic Health. H.C.K. is a stockholder of Theraclion SA and Phaon scientific. O.H. received honoraria from Riemser, Roche, Amgen, Pfizer, Eisai, Hexal, MSD, Daiichi Sankyo, and Novartis. R.K. has received honoraria from Tesaro and AstraZeneca in the last 3 years, is part of the advisory board from Medtronic and council of IGCS and president of SERGS, and proctored and presented for Intuitive Surgical. S.K.B. is a consultant for QIAGEN, Hilden, Germany. The remaining author M.T. declares that she has no competing interests.