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Article History

Received: 15 February 2021

Accepted: 5 January 2022

First Online: 25 January 2022

Declarations

:

: All research forming the basis of this study was conducted in accordance to relevant rules, regulations, and guidelines and conform to the principles of the Declaration of Helsinki. For samples included in the discovery cohort, written consent was obtained from all participants prior to their donation of tissue samples for a research biobank (approved by The Central Denmark Region Committees on Health Research Ethics [jr. nr. 2000-0299] and The Danish Data Protection Agency [jr. nr. 2013-41-2041 and jr. nr. 2007-58-0010]). The present study was approved by the Danish National Committee on Health Research Ethics [jr. nr. 1302791 and jr. nr. 1603542], who waived the requirement for patient consent, as (1) the new analyses were considered to not pose any health risk or other significant disadvantages to the participants and (2) an expert committee was established to deal with potential (although unlikely) incidental genetic findings in this new study.

: Not applicable

: The authors declare that they have no competing interests.