Crossmark

DrABC: deep learning accurately predicts germline pathogenic mutation status in breast cancer patients based on phenotype data

Crossref DOI link: https://doi.org/10.1186/s13073-022-01027-9

Published Online: 2022-02-25

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Liu, Jiaqi

Zhao, Hengqiang

Zheng, Yu

Dong, Lin

Zhao, Sen

Huang, Yukuan

Huang, Shengkai

Qian, Tianyi

Zou, Jiali

Liu, Shu

Li, Jun

Yan, Zihui

Li, Yalun

Zhang, Shuo

Huang, Xin

Wang, Wenyan

Li, Yiqun

Wang, Jie

Ming, Yue

Li, Xiaoxin

Xing, Zeyu

Qin, Ling

Zhao, Zhengye

Jia, Ziqi

Li, Jiaxin

Liu, Gang

Zhang, Menglu

Feng, Kexin

Wu, Jiang

Zhang, Jianguo

Yang, Yongxin

Wu, Zhihong

Liu, Zhihua

Ying, Jianming

Wang, Xin

Su, Jianzhong

Wang, Xiang

Wu, Nan http://orcid.org/0000-0002-9429-2889
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (81802669, 61871294, 81472046 and 81772299, 81501852 and 82072391)

Natural Science Foundation of Beijing Municipality (JQ20032)

Tsinghua University-Peking Union Medical College Hospital Initiative Scientific Research Program

the PUMC Youth Fund & the Fundamental Research Funds for the Central Universities (No.3332019052)

Natural Science Foundation of Zhejiang Province (LR19C060001)

Fundamental Research Funds for Wenzhou Institute of University of Chinese Academy of Sciences (WIBEZD2017009-05)

the CAMS Innovation Fund for Medical Sciences (2020-I2M-C&T-B-068, 2020-I2M-C&T-A-015, 2021-I2M-1-051, 2021-I2M-1-052)

the Beijing Hope Run Special Fund (LC2020B05)

Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences (2019PT320025)
License Information

Text and Data Mining valid from 2022-02-25

Version of Record valid from 2022-02-25
More Information

Article History

Received: 21 December 2020

Accepted: 10 February 2022

First Online: 25 February 2022

Declarations

:

: This study was reviewed and approved by the ethics committees at the Cancer Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College (the main patient source, reference number: 2021041314383902) and other six hospitals, including (1) Huanxing Cancer Hospital, (2) Guiyang Maternal and Child Healthcare Hospital in Guiyang, (3) the Affiliated Cancer Hospital of Zhengzhou University, (4) the Affiliated Yantai Yuhuangding Hospital of Qingdao University, (5) the Fourth Hospital of Hebei Medical University, and (6) Beijing Tiantan Hospital all in China. This study conformed to the principles of the Helsinki Declaration. Written informed consent was obtained from each participant.

: Patients in this study gave consent to publish variant information.

: The authors declare that they have no competing interests.

Document is current

Any future updates will be listed below