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Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury

Crossref DOI link: https://doi.org/10.1186/s13073-022-01108-9

Published Online: 2022-09-09

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Hinze, Christian http://orcid.org/0000-0003-2526-1621
Kocks, Christine http://orcid.org/0000-0003-1749-3334
Leiz, Janna http://orcid.org/0000-0002-6531-7047
Karaiskos, Nikos

Boltengagen, Anastasiya

Cao, Shuang

Skopnik, Christopher Mark http://orcid.org/0000-0002-6089-4769
Klocke, Jan http://orcid.org/0000-0002-7723-9234
Hardenberg, Jan-Hendrik http://orcid.org/0000-0001-9548-2118
Stockmann, Helena http://orcid.org/0000-0002-0934-7620
Gotthardt, Inka http://orcid.org/0000-0001-6033-0093
Obermayer, Benedikt http://orcid.org/0000-0002-9116-630X
Haghverdi, Laleh

Wyler, Emanuel

Landthaler, Markus http://orcid.org/0000-0002-1075-8734
Bachmann, Sebastian

Hocke, Andreas C. http://orcid.org/0000-0002-6935-8612
Corman, Victor

Busch, Jonas

Schneider, Wolfgang

Himmerkus, Nina http://orcid.org/0000-0002-2910-6728
Bleich, Markus http://orcid.org/0000-0002-1745-2295
Eckardt, Kai-Uwe http://orcid.org/0000-0003-3823-0920
Enghard, Philipp http://orcid.org/0000-0002-7254-3931
Rajewsky, Nikolaus http://orcid.org/0000-0002-4785-4332
Schmidt-Ott, Kai M. http://orcid.org/0000-0002-7700-7142
Funding

Funding for this research was provided by:

Deutsche Forschungsgemeinschaft (SFB 1365, GRK 2318, FOR 2841, HI-2238/2-1, SFB-TR 84, B6 / Z1a, EN 924/5-1, RA 838/5-1, KA 5006/1-1, Gottfried Wilhelm Leibniz Prize)

Berlin Institute of Health (Focus Area Translational Vascular Biomedicine, COVID Startup funding)

Berlin University Alliance GC2 Global Health (Corona Virus Pre-Exploration Project)

Bundesministerium für Bildung und Forschung ((RAPID, Organo-Strat 01KX2021)

Dr. Werner Jackstädt-Stiftung
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Article History

Received: 11 January 2022

Accepted: 12 August 2022

First Online: 9 September 2022

Declarations

:

: Our study protocol was approved by Charité’s Ethics Committee (ethics approvals EA2/045/18 for post mortem kidney biopsies and EA4/026/18 for tumor-adjacent normal tissue) and was conducted by following the Declaration of Helsinki and Guidelines for Good Clinical Practice. Written informed consent was given by the next of kin before enrollment in our study.

: Not applicable.

: The authors declare no competing interests.

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