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Authors
Ward, Joseph C. https://orcid.org/0009-0000-8319-6464
Soriano, Ignacio https://orcid.org/0000-0002-7928-3511
Thorn, Steve https://orcid.org/0000-0002-9962-9356
Fernández-Tajes, Juan https://orcid.org/0000-0003-1515-2421
Sherwood, Kitty https://orcid.org/0009-0007-4055-607X
Gül, Güler https://orcid.org/0009-0008-5057-4957
Scheffers, Joost
Frangou, Anna https://orcid.org/0000-0001-6990-2756
Kinnersley, Ben https://orcid.org/0000-0003-1783-6296
Kafetzopoulos, Ioannis https://orcid.org/0000-0001-5948-3455
Sproul, Duncan https://orcid.org/0000-0001-6168-4563
Galavotti, Sara https://orcid.org/0000-0002-1240-0963
Palles, Claire https://orcid.org/0000-0002-9670-2263
Gruber, Andreas J. https://orcid.org/0000-0001-7664-4257
Church, David N. https://orcid.org/0000-0002-4617-962X
Tomlinson, Ian https://orcid.org/0000-0003-3037-1470
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Funding
Funding for this research was provided by:
Wellcome Trust (210804/B/18/Z)
Cancer Research UK (CA6199/A27327)
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Article History
Received: 26 February 2025
Accepted: 1 August 2025
First Online: 25 August 2025
Declarations
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: The Genomics England National Genomic Research Library is a research resource with approval to operate as a Research Tissue Bank by the HRA/Cambridge Central Research Ethics Committee (REC reference 20/EE/0035), with the core principles of the Declaration of Helsinki embedded into day-to-day operations. All 100kGP cancer whole-genome sequencing data used in this study can be accessed within the secure Genomics England Research Environment, subject to institutional agreements (see the Data Availability statement below).
: Not applicable.
: The authors declare no competing interests.
